Metformin is a biguanide oral hypoglycemic agent. Metformin is used in the treatment of polycystic ovary syndrome and in other diseases where insulin resistance may be an important factor. Glucophage does not cause hypoglycemia when used alone. Glucophage is not used in type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis. Metformin promotes peripheral glucose utilization by enhancing anaerobic glycolysis. Metformin helps reduce LDL cholesterol and triglyceride levels and is not associated with weight gain. Glucophage is the only anti-diabetic drug that has been conclusively shown to prevent the cardiovascular complications of diabetes. Metformin treatment for type 2 diabetes may decrease their chances of developing the disease. When you buy Glocophage online from our pharmacy, you are assured of the highest quality generic drug at the lowest prices. Buy Glucophage online from us take advantage of the heavy volume discounts we offer with every purchase. Learn More
Exp. Date: July 2014 (Last Updated: Nov 21, 2011)
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| Manufacturer: Cipla |
Average Delivery Time: 12-21 Business Days |
| Brand Name: Glucophage |
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Generic Glucophage Pills
| Quantity |
Strength |
Price / Pill |
Price |
|
| 30 Tab(s) |
500mg |
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FAQ about Generic Glucophage
How does Glucophage work?
Metformin does not increase the levels of insulin in blood. Metformin suppresses hepatic glucose production and glucose output from liver. Metformin activates AMP-activated protein kinase (AMPK), a liver enzyme that plays an important role in insulin signaling and the metabolism of glucose and fats.
Side effects of Metformin
The common side effects reported with Glucophage are gastrointestinal upset, diarrhea, cramps, increased flatulence, shakiness, sweating, nervousness, sudden changes in mood, head ache, numbness, weakness, pale skin, hunger, jerky movements, nausea, vomiting, asthenia, indigestion, abdominal discomfort and head ache.
Guidelines before using Glucophage
Metformin is contraindicated in people with kidney disorders, lung disease and liver disease. Acute congestive heart failure increases risk of lactic acidosis with metformin. It is recommended that metformin be temporarily discontinued before any radiographic study involving iodinated contrast as contrast dye may temporarily impair kidney function, indirectly leading to lactic acidosis by causing retention of metformin in the body. It is recommended that metformin be resumed only after two days. Glucophage should be taken with meals to reduce gastrointestinal side effects of Metformin. Metformin can cause lactic acidosis leading to hypoxic states and impairment of renal function. Metformin should not be administered in pregnant women and breast feeding mothers unless clearly indicated. The H2-receptor antagonist cimetidine causes an increase in the plasma concentration of metformin. The patient should be advised to avoid alcohol intake while on Metformin treatment as alcohol potentiates lactic acidosis Glucophage is not indiacted in pediatric patients below the age of 10. Cimetidine increases the levels of Metformin in blood.
What are the common dosages of Metformin?
The recommended starting dosage of Glucophage is 500mg twice daily. Glucophage can be taken with meals two or three times a day. The recommended starting dose of Metformin in pediatric patients (10-16 years of age) is 500mg twice daily. The dose of Metformin is gradually increased, not more often than once every 1-2 weeks. The maximum tolerated dose is 2550mg daily in adults and 2000mg in pediatric patients.
Difference between Brand and Generic Glucophage
Generic Glucophage is as good as its brand counterpart when it comes to the effectiveness. The noticeable differences are in the shape, size and packaging. The other major difference is in the price. You can buy cheap Glucophage when it is sold as a generic drug. With rising health costs, especially that of drugs, Generic Glucophage is definitely a better option since you get all the benefits of the brand but at fraction of the cost of a brand.
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