Colchicine possesses cathartic and emetic effects. The axoplasmic transport in neurones is disrupted by colchicine. The therapeutic value of colchicine against cancer is limited by its toxicity against normal cells. Colchicine can also be used as initial treatment for pericarditis and to prevent recurrences of the condition. Colchicine combined with the anti-inflammatory drug olsalazine is used in the treatment of constipation-predominant irritable bowel syndrome. Colchicine has a relatively low therapeutic index. When you buy Colchicine online from our pharmacy, you are assured of the highest quality generic drug at the lowest prices. Buy Colchicine online from us and join thousands of other satisfied customers.
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| Manufacturer: |
Average Delivery Time: 12-21 Business Days |
| Brand Name: Colchicine |
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Generic Colchicine
| Quantity |
Strength |
Price |
|
| 60 Tab(s) |
0.5mg |
$25.25 |
|
| 120 Tab(s) |
0.5mg |
$44.17 |
|
| 180 Tab(s) |
0.5mg |
$65.18 |
|
FAQ about Generic Colchicine
How does Colchicine work?
Colchicine inhibits microtubule polymerization by binding to tubulin. The presence of tubulin is essential to mitosis, and therefore colchicine effectively functions as a "mitotic poison" or spindle poison. The anti inflammatory action is due to the inhibition of neutrophil activity. Colchicine also inhibits the deposition of uric acid (urate) crystals. The formation of urate crystals is enhanced by a low pH in the tissues. Colchicine raises the tissue pH by inhibiting the oxidation of glucose, thereby reducing the production of lactic acid in leukocytes. The inhibition of uric acid crystals is a vital aspect of the mechanism of gout treatment.
Side effects of Colchicine
The common side effects reported with Colchicine are gastro-intestinal upset, anemia, nausea, stomach pain, vomiting, diarrhea, yellowing eyes or skin, sore throat, easy bruising or bleeding, muscle aches, numbness or tingling of legs and arms, fatigue, rash, itchy skin and neutropenia.
Guidelines before using Colchicine
Long term prophylactic regimens of oral colchicine are absolutely contraindicated in patients with advanced renal failure as it results in severe neuromyopathy. Alcohol can decrease the effectiveness of Colchicine. Limit alcohol consumption while taking Colchicine. Colchicine is not recommended for use during pregnancy. Chronic therapy with Colchicine is not recommended because it causes aplastic anemia, agranulocytosis, myopathy and loss of hair.
What are the common dosages of Colchicine?
The dose of Colchicine for the treatment of gout is 1mg orally followed by 0.25mg 1-3 hourly till control of attack is achieved. The maintenance dose of 0.5-1mg is given for 4-8 weeks in which time control of hyperuricemia is achieved with other drugs. Colchicine 0.5-1.5mg/day can prevent further attack of gouts.
Difference between Brand and Generic Colchicine
Generic Colchicine is the chemical equivalent of the brand but manufactured only after the patent of the brand has expired. There is no difference in the action of brand and generic Colchicine. The active ingredient, Colchicine, is the same in both brand and generic versions. However the filler ingredients will differ. The other noticeable difference is the price. You can buy cheap Colchicine when it is sold as a generic variant.
Where and How to buy Colchicine
You can now buy Colchicine online from our online pharmacy. When you order Colchicine from us, you can be assured of a hassle free delivery at your doorstep. Purchase Colchicine from us and enjoy the volume discounts we offer all year through. Buy Colchicine online from us and be assured about the quality and safety of generic drugs.
Why is the price of Colchicine so cheap at Qualitygenerics.com?
The bulk of the price of a drug is attributable to the developmental expenses. Since generic drugs are manufactured based on the formula already developed, there are no developmental expenses involved. Also it is not a new drug and hence there are no major marketing expenses involved. Due to these factors you can buy cheap Colchicine online from Qualitygenerics.com without compromising on the quality of the drug.
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